Literature summary extracted from

Abell, A.D.; Nabbs, B.K.
Ring-deactivated hydroxymethylpyrroles as inhibitors of alpha-chymotrypsin (2001), Bioorg. Med. Chem., 9, 621-628.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.21.1	2-hydroxymethyl-1-(2-phenylethanecarbonyl)pyrrole	0.0125 mg/ml, 10% inhibition	Bos taurus
3.4.21.1	2-hydroxymethyl-1-(2-phenylethansulfonyl)pyrrole	0.0125 mg/ml, 15% inhibition	Bos taurus
3.4.21.1	2-hydroxymethyl-1-(2-phenylethenylsulfonyl)pyrrole	0.0125 mg/ml, 15% inhibition	Bos taurus
3.4.21.1	2-hydroxymethyl-1-(N-phthalyl-L-leucine)pyrrole	0.0125 mg/ml, 10% inhibition	Bos taurus
3.4.21.1	2-hydroxymethyl-1-(phenylsulfonyl)pyrrole	0.053 mM, 20% inhibition	Bos taurus
3.4.21.1	methyl-4-hydroxy-4-[1-(phenylsulfonyl)pyrrol-2-yl]butanoate	0.0125 mg/ml, 10% inhibition	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.1	Bos taurus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.21.1	N-succinyl-L-Phe-p-nitroanilide + H2O	-	Bos taurus	N-succinyl-L-Phe + p-nitroaniline	-	?

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Release 2023.1 (January 2023)