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Literature summary extracted from

  • Chung, S.J.; Kim, D.H.
    N-(Hydroxyaminocarbonyl)phenylalanine: a novel class of inhibitor for carboxypeptidase A (2001), Bioorg. Med. Chem., 9, 185-189.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.1 3-hydroxyaminocarbonyl-2-benzylpropanoic acid
-
 Bos taurus
3.4.17.1 D-N-(hydroxyaminocarbonyl)phenylalanine
-
 Bos taurus
3.4.17.1 L-N-(aminocarbonyl)phenylalanine
-
 Bos taurus
3.4.17.1 L-N-(hydroxyaminocarbonyl)phenylalanine
-
 Bos taurus
3.4.17.1 additional information no inhibition by N-(aminocarbonyl)phenylalanine up to 3.6 mM Bos taurus
3.4.17.1 rac-2-benzyl-3-mercaptopropanoic acid
-
 Bos taurus
3.4.17.1 rac-N-(aminocarbonyl)phenylalanine
-
 Bos taurus
3.4.17.1 rac-N-(hydroxyaminocarbonyl)phenylalanine
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.1 Bos taurus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.1 hippuryl-Phe + H2O
-
 Bos taurus hippuric acid + Phe
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.17.1 0.000011
-
 rac-2-benzyl-3-mercaptopropanoic acid pH 7.5, pH 25°C Bos taurus
3.4.17.1 0.00154
-
 D-N-(hydroxyaminocarbonyl)phenylalanine pH 7.5, 25°C Bos taurus
3.4.17.1 0.00209
-
 rac-N-(hydroxyaminocarbonyl)phenylalanine pH 7.5, 25°C Bos taurus
3.4.17.1 0.00456
-
 L-N-(hydroxyaminocarbonyl)phenylalanine pH 7.5, 25°C Bos taurus
3.4.17.1 0.01898
-
 L-N-(aminocarbonyl)phenylalanine pH 7.5, 25°C Bos taurus
3.4.17.1 0.0242
-
 3-hydroxyaminocarbonyl-2-benzylpropanoic acid pH 7.5, 25°C Bos taurus
3.4.17.1 0.0585
-
 rac-N-(aminocarbonyl)phenylalanine pH 7.5, 25°C Bos taurus