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Literature summary extracted from

  • Lee, M.; Kim, D.H.
    Hippuryl-alpha-methylphenylalanine and hippuryl-alpha-methylphenyllactic acid as substrates for carboxypeptidase A. Syntheses, kinetic evaluation and mechanistic implication (2000), Bioorg. Med. Chem., 8, 815-823.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.1 (R)-hippuryl-alpha-MePhe
-
Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.17.1 0.072
-
(S)-hippuryl-OPhe pH 7.5 Bos taurus
3.4.17.1 0.313
-
(S)-hippuryl-alpha-MePhe pH 7.5 Bos taurus
3.4.17.1 0.344
-
(S)-hippuryl-alpha-methylphenyllactic acid pH 7.5 Bos taurus
3.4.17.1 0.7
-
hippuryl-Phe pH 7.5 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.1 Bos taurus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.1 (S)-hippuryl-alpha-MePhe + H2O
-
Bos taurus ?
-
?
3.4.17.1 (S)-hippuryl-alpha-methylphenyllactic acid + H2O
-
Bos taurus ?
-
?
3.4.17.1 (S)-hippuryl-OPhe + H2O
-
Bos taurus ?
-
?
3.4.17.1 hippuryl-Phe + H2O
-
Bos taurus hippuric acid + Phe
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.17.1 0.33
-
(S)-hippuryl-alpha-MePhe pH 7.5 Bos taurus
3.4.17.1 81
-
hippuryl-Phe pH 7.5 Bos taurus
3.4.17.1 477
-
(S)-hippuryl-alpha-methylphenyllactic acid pH 7.5 Bos taurus
3.4.17.1 682
-
(S)-hippuryl-OPhe pH 7.5 Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.17.1 0.405
-
(R)-hippuryl-alpha-MePhe pH 7.5 Bos taurus