Any feedback?
Literature summary extracted from
- Synthesis and evaluation of alpha,alpha-disubstituted-3-mercaptopropanoic acids as inhibitors for carboxypeptidase A and implications with respect to enzyme inhibitor design (2003), Bioorg. Med. Chem., 11, 4685-4691.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.1 | (R)-2-mercaptomethyl-2-methyl-3-phenylpropanoic acid | - |
Bos taurus |  |
| 3.4.17.1 | (RS)-2-mercaptomethyl-2-methyl-3-phenylpropanoic acid | - |
Bos taurus | |
| 3.4.17.1 | (RS)-2-mercaptomethyl-2-methylbutanoic acid | - |
Bos taurus | |
| 3.4.17.1 | (RS)-2-mercaptomethylbutyric acid | - |
Bos taurus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.17.1 | Bos taurus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.17.1 | hippuryl-L-Phe + H2O | - |
Bos taurus | hippuric acid + L-Phe | - |
? | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.17.1 | 0.0001 | - |
(RS)-2-mercaptomethylbutyric acid | pH 7.5 | Bos taurus | |
| 3.4.17.1 | 0.00011 | - |
(RS)-2-mercaptomethyl-2-methylbutanoic acid | pH 7.5 | Bos taurus | |
| 3.4.17.1 | 0.00038 | - |
(RS)-2-mercaptomethyl-2-methyl-3-phenylpropanoic acid | pH 7.5 | Bos taurus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
