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Literature summary extracted from

  • Piacentini, M.P.; Piatti, E.; Fraternale, D.; Ricci, D.; Albertini, M.C.; Accorsi, A.
    Phospholipase C-dependent phosphoinositide breakdown induced by ELF-EMF in Peganum harmala calli (2004), Biochimie, 86, 343-349.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.11 additional information extremely low frequency electromagnetic fields affect the phosphoinositide signal transduction pathway by triggering the PI-PLC activation and the consequent phosphatidylinositol 4,5-bisphosphate breakdown Peganum harmala

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.11 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine potent inhibitor Peganum harmala
3.1.4.11 neomycin
-
 Peganum harmala
3.1.4.11 U-73122
-
 Peganum harmala

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O Peganum harmala part of the phosphoinositide signal transduction pathway 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.11 Peganum harmala
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.11 callus 20 days old calli Peganum harmala
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
-
 Peganum harmala 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O part of the phosphoinositide signal transduction pathway Peganum harmala 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?