EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.4 | LEKTI | the LEKI gene encodes a 15-domain serine proteinase inhibitor, disulfide bonds are important for LEKTI function, noncompetitive mechanism, expression and purification of human LEKTI gene in Sf9 | Homo sapiens | |
3.4.21.7 | LEKTI | potent noncompetitive inhibitor, recombinant LEKTI is purified using a baculovirus/insect cell expression system | Homo sapiens | |
3.4.21.62 | human LEKTI | noncompetitive inhibition | Bacillus licheniformis |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.4 | 0.485 | - |
Glu-Gly-Arg-4-nitroanilide | pH 7.4, 25°C | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.4 | Homo sapiens | - |
- |
- |
3.4.21.7 | Homo sapiens | - |
- |
- |
3.4.21.62 | Bacillus licheniformis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.4 | Glu-Gly-Arg-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.62 | succinyl-AAPF-p-nitroanilide + H2O | - |
Bacillus licheniformis | succinyl-AAPF + p-nitroaniline | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.4 | 0.000849 | - |
LEKTI | pH 7.4, 25°C | Homo sapiens | |
3.4.21.7 | 0.000027 | - |
LEKTI | - |
Homo sapiens | |
3.4.21.62 | 0.000049 | - |
human LEKTI | pH 7.4, 25°C | Bacillus licheniformis |