Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jackson, L.K.; Brooks, H.B.; Myers, D.P.; Phillips, M.A.
    Ornithine decarboxylase promotes catalysis by binding the carboxylate in a buried pocket containing phenylalanine 397 (2003), Biochemistry, 42, 2933-2940.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.17 expression in Escherichia coli Trypanosoma brucei

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.17 F397A 0.6% of wild-type activity Trypanosoma brucei

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.17 0.5
-
 L-ornithine
-
 Trypanosoma brucei

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.17 L-ornithine Trypanosoma brucei
-
 putrescine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Trypanosoma brucei P07805
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.17 recombinant ODC Trypanosoma brucei

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-ornithine
-
 Trypanosoma brucei putrescine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.17 ODC
-
 Trypanosoma brucei

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.1.17 9.4
-
 L-ornithine
-
 Trypanosoma brucei

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.17 pyridoxal 5'-phosphate
-
 Trypanosoma brucei