BRENDA - Enzyme Database

Role of metal ions in catalysis by enolase: an ordered kinetic mechanism for a single substrate enzyme

Poyner, R.R.; Cleland, W.W.; Reed, G.H.; Biochemistry 40, 8009-8017 (2001)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.11
3-hydroxy-2-nitro-1-phosphonopropane
-
Saccharomyces cerevisiae
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
4.2.1.11
Mg2+
two ions are necessary for activity, shows inhibition at high concentration
Saccharomyces cerevisiae
4.2.1.11
Mn2+
can replace Mg2+, mechanistic study using electron paramagnetic resonance
Saccharomyces cerevisiae
4.2.1.11
Zn2+
can replace Mg2+, mechanistic study using electron paramagnetic resonance
Saccharomyces cerevisiae
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Saccharomyces cerevisiae
P00924
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
650084
Saccharomyces cerevisiae
phosphoenolpyruvate
-
650084
Saccharomyces cerevisiae
r
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.11
3-hydroxy-2-nitro-1-phosphonopropane
-
Saccharomyces cerevisiae
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
4.2.1.11
Mg2+
two ions are necessary for activity, shows inhibition at high concentration
Saccharomyces cerevisiae
4.2.1.11
Mn2+
can replace Mg2+, mechanistic study using electron paramagnetic resonance
Saccharomyces cerevisiae
4.2.1.11
Zn2+
can replace Mg2+, mechanistic study using electron paramagnetic resonance
Saccharomyces cerevisiae
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
650084
Saccharomyces cerevisiae
phosphoenolpyruvate
-
650084
Saccharomyces cerevisiae
r