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Literature summary extracted from

  • Bergstrom, J.D.; Edmond, J.
    A radiochemical assay for acetoacetyl-CoA synthetase (1985), Anal. Biochem., 149, 358-364.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.2.1.16 phosphate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.16 0.07
-
 acetoacetate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.16 cytosol
-
 Homo sapiens 5829
-
6.2.1.16 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.16 Homo sapiens
-
-
-
6.2.1.16 Rattus norvegicus
-
-
-
6.2.1.16 Zoogloea ramigera
-
-
-
6.2.1.16 Zoogloea ramigera 1-16-M / ATCC 19623
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.16 fibroblast
-
 Homo sapiens
-
6.2.1.16 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.16 ATP + acetoacetate + CoA
-
 Homo sapiens AMP + diphosphate + acetoacetyl-CoA
-
 ?
6.2.1.16 ATP + acetoacetate + CoA
-
 Rattus norvegicus AMP + diphosphate + acetoacetyl-CoA
-
 ?
6.2.1.16 ATP + acetoacetate + CoA
-
 Zoogloea ramigera AMP + diphosphate + acetoacetyl-CoA
-
 ?
6.2.1.16 ATP + acetoacetate + CoA
-
 Zoogloea ramigera 1-16-M / ATCC 19623 AMP + diphosphate + acetoacetyl-CoA
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.16 7.5
-
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
6.2.1.16 6 9 pH 6.0: about 30% of maximal activity, pH 9.0: about 65% of maximal activity Rattus norvegicus