Literature summary extracted from

Lee, L.V.; Vu, M.V.; Cleland, W.W.
13C and deuterium isotope effects suggest an aldol cleavage mechanism for L-ribulose-5-phosphate 4-epimerase (2000), Biochemistry, 39, 4808-4820.

Protein Variants

EC Number	Protein Variants	Comment	Organism
5.1.3.4	H97N	13C isotope effects at pH 7 are 3.25% at C-3 and 2.69% at C4, compared to 1.85% and 1.5% for the wild-type enzyme	Escherichia coli
5.1.3.4	Y229F	13C isotope effects at pH 7 are 2.53% at C-3 and 1.99% at C4, compared to 1.85% and 1.5% for the wild-type enzyme	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.1.3.4	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.1.3.4	L-Ribulose 5-phosphate	aldol cleavage mechanism	Escherichia coli	D-Xylulose 5-phosphate	-	?

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Release 2023.1 (January 2023)