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Literature summary extracted from

  • Radfar, R.; Shin, R.; Sheldrick, G.M.; Minor, W.; Lovell, C.R.; Odom, J.D.; Dunlap, R.B.; Lebioda, L.
    The crystal structure of N(10)-formyltetrahydrofolate synthetase from Moorella thermoacetica (2000), Biochemistry, 39, 3920-3926.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.4.3 expression in Escherichia coli Moorella thermoacetica

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
6.3.4.3 Se-Met FTHFS is crystallized by hanging-drop vapor-diffusion, crystals diffract to 2.5 A Moorella thermoacetica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.4.3 ATP + formate + tetrahydrofolate Moorella thermoacetica
-
 ADP + phosphate + 10-formyltetrahydrofolate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.3 Moorella thermoacetica P21164 previously referred to as Clostridium thermoaceticum
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.4.3 recombinant FTHFS, heparin Agarose, Phenyl Sepharose Moorella thermoacetica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.3 ATP + formate + tetrahydrofolate
-
 Moorella thermoacetica ADP + phosphate + 10-formyltetrahydrofolate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.4.3 FTHFS
-
 Moorella thermoacetica