EC Number | Cloned (Comment) | Organism |
---|---|---|
4.4.1.5 | - |
Homo sapiens |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
4.4.1.5 | crystal sructure of glyoxalase I in complex with S-(N-hydroxy-N-p-bromophenylcarbamoyl)glutathione and S-p-nitrobenzyloxycarbonylglutathione at 2.0 and 1.72 A, respectively | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.5 | S-(N-hydroxy-N-methylcarbamoyl)glutathione | - |
Homo sapiens | |
4.4.1.5 | S-(N-hydroxy-N-p-bromophenylcarbamoyl)glutathione | - |
Homo sapiens | |
4.4.1.5 | S-(N-hydroxy-N-p-iodophenylcarbamoyl)glutathione | - |
Homo sapiens | |
4.4.1.5 | S-p-bromobenzylglutathione | - |
Homo sapiens | |
4.4.1.5 | S-p-nitrobenzyloxycarbonylglutathione | - |
Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.5 | Zn2+ | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.4.1.5 | glutathione-methylglyoxal hemithioacetal | Homo sapiens | glutathione-methylglyoxal hemithioacetal is formed non-enzymatically from methylglyoxal and glutathione | (R)-S-lactoylglutathione | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.4.1.5 | Homo sapiens | Q04760 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.4.1.5 | - |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.4.1.5 | glutathione-methylglyoxal hemithioacetal | glutathione-methylglyoxal hemithioacetal is formed non-enzymatically from methylglyoxal and glutathione | Homo sapiens | (R)-S-lactoylglutathione | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.4.1.5 | glyoxalase I | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.4.1.5 | 0.000014 | - |
S-(N-hydroxy-N-p-bromophenylcarbamoyl)glutathione | - |
Homo sapiens | |
4.4.1.5 | 0.00008 | - |
S-p-bromobenzylglutathione | - |
Homo sapiens |