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Literature summary extracted from

  • Sato, H.; Takahashi, N.; Nakamoto, M.; Ohgami, M.; Yamazaki, M.; Fukui, T.
    Effects of streptozotocin-induced diabetes on acetoacetyl-CoA synthetase activity in rats (2002), Biochem. Pharmacol., 63, 1851-1855.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.16 Rattus norvegicus
-
 female, Sprague-Dawley strain
-
6.2.1.16 Rattus norvegicus Sprague-Dawley
-
 female, Sprague-Dawley strain
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.2.1.16 additional information
-
 streptozotocin-induced diabetes results in a decrease in acetoacetyl-CoA synthetase specific activity in rat liver, but not in other acetoacetyl-CoA synthetase containing tissues, e.g kidney, lung or brain, hepatic acetoacetyl-CoA synthetase activity is 8fold higher in rats fed with cholestyramine and pravastatin Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.16 ATP + acetoacetate + CoA
-
 Rattus norvegicus AMP + diphosphate + acetoacetyl-CoA
-
 ?
6.2.1.16 ATP + acetoacetate + CoA
-
 Rattus norvegicus Sprague-Dawley AMP + diphosphate + acetoacetyl-CoA
-
 ?