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Literature summary extracted from
- Purification and characterization of a phospholipase A2 isoenzyme isolated from Lachesis muta snake venom (2002), Biochem. Pharmacol., 63, 1589-1597.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.4 | 4-bromophenacyl bromide | abolishes inhibitory effect upon collagen- and ADP-induced platelet aggregation and the edematogenic effect | Lachesis muta |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 18000 | - |
- |
Lachesis muta |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.4 | additional information | Lachesis muta | inhibits platelet aggregation induced by collagen and ADP | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.4 | Lachesis muta | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.1.4 | - |
Lachesis muta |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.4 | venom | - |
Lachesis muta | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | additional information | - |
- |
Lachesis muta |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.4 | additional information | inhibits platelet aggregation induced by collagen and ADP | Lachesis muta | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.4 | LM-PLA2-I | - |
Lachesis muta |
| 3.1.1.4 | LM-PLA2-II | - |
Lachesis muta |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 3.1.1.4 | Lachesis muta | isoform lm-PLA2-I, isoelectric focusing, pH gradient pH 2.5-6.5 and pH 3-10 | 4.8 | 4.7 |
| 3.1.1.4 | Lachesis muta | isoform lm-PLA2-II, isoelectric focusing, pH gradient pH 2.5-6.5 and pH 3-10 | - |
5.4 |
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Release 2023.1 (January 2023)
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