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Literature summary extracted from

  • Deng, H.; Huang, A.; So, S.P.; Lin, Y.Z.; Ruan, K.H.
    Substrate access channel topology in membrane-bound prostacyclin synthase (2002), Biochem. J., 362, 545-551.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.99.4 expression in Cos-1 cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.99.4 endoplasmic reticulum
-
 Homo sapiens 5783
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.99.4 57000
-
 x * 57000, deduced from nucleotide sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.99.4 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate Homo sapiens i.e. prostaglandin H2 (5Z,13E)-(15S)-6,9alpha-epoxy-11a,15-dihydroxyprosta-5,13-dienoate prostaglandin I2 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.4 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.4 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate i.e. prostaglandin H2 Homo sapiens (5Z,13E)-(15S)-6,9alpha-epoxy-11a,15-dihydroxyprosta-5,13-dienoate prostaglandin I2 ?

Subunits

EC Number Subunits Comment Organism
5.3.99.4 ? x * 57000, deduced from nucleotide sequence Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
5.3.99.4 PGIS
-
 Homo sapiens
5.3.99.4 prostacyclin synthase
-
 Homo sapiens