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Literature summary extracted from

  • Yoshida, Y.; Negishi, M.; Amano, A.; Oho, T.; Nakano, Y.
    Differences in the betaC-S lyase activities of viridans group streptococci (2002), Biochem. Biophys. Res. Commun., 300, 55-60.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.4.1.1 medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus mutans
4.4.1.1 medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus salivarius
4.4.1.1 medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus oralis
4.4.1.1 medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus sobrinus
4.4.1.1 medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus gordonii
4.4.1.1 medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus anginosus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.1 0.68
-
 L-cysteine pH 7.6, 37°C Streptococcus gordonii
4.4.1.1 0.75
-
 L-cysteine pH 7.6, 37°C Streptococcus sobrinus
4.4.1.1 0.88
-
 L-cysteine pH 7.6, 37°C Streptococcus anginosus
4.4.1.1 1.08
-
 L-cysteine pH 7.6, 37°C Streptococcus oralis
4.4.1.1 1.16
-
 L-cysteine pH 7.6, 37°C Streptococcus salivarius
4.4.1.1 2.46
-
 L-cysteine pH 7.6, 37°C Streptococcus mutans
4.4.1.1 8.7
-
 L-cystathionine pH 7.6, 37°C Streptococcus gordonii
4.4.1.1 10.6
-
 L-cystathionine pH 7.6, 37°C Streptococcus sobrinus
4.4.1.1 11.1
-
 L-cystathionine pH 7.6, 37°C Streptococcus anginosus
4.4.1.1 11.2
-
 L-cystathionine pH 7.6, 37°C Streptococcus oralis
4.4.1.1 11.8
-
 L-cystathionine pH 7.6, 37°C Streptococcus mutans
4.4.1.1 25.5
-
 L-cystathionine pH 7.6, 37°C Streptococcus salivarius

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus mutans
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus salivarius
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus oralis
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus sobrinus
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus gordonii
4.4.1.1 44000
-
 x * 44000, SDS-PAGE Streptococcus anginosus

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Streptococcus anginosus
-
-
-
4.4.1.1 Streptococcus gordonii
-
-
-
4.4.1.1 Streptococcus mutans
-
-
-
4.4.1.1 Streptococcus oralis
-
-
-
4.4.1.1 Streptococcus salivarius
-
-
-
4.4.1.1 Streptococcus sobrinus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cystathione + H2O
-
 Streptococcus mutans L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cystathione + H2O
-
 Streptococcus salivarius L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cystathione + H2O
-
 Streptococcus oralis L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cystathione + H2O
-
 Streptococcus sobrinus L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cystathione + H2O
-
 Streptococcus gordonii L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cystathione + H2O
-
 Streptococcus anginosus L-cysteine + NH3 + 2-oxobutanoate
-
 ?
4.4.1.1 L-cystathionine + H2O
-
 Streptococcus mutans L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cystathionine + H2O
-
 Streptococcus salivarius L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cystathionine + H2O
-
 Streptococcus oralis L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cystathionine + H2O
-
 Streptococcus sobrinus L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cystathionine + H2O
-
 Streptococcus gordonii L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cystathionine + H2O
-
 Streptococcus anginosus L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus mutans sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus salivarius sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus oralis sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus sobrinus sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus gordonii sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Streptococcus anginosus sulfide + NH3 + pyruvate
-
 ?

Subunits

EC Number Subunits Comment Organism
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus mutans
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus salivarius
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus oralis
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus sobrinus
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus gordonii
4.4.1.1 ? x * 44000, SDS-PAGE Streptococcus anginosus