Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tobimatsu, T.; Kajiura, H.; Toraya, T.
    Specificities of reactivating factors for adenosylcobalamin-dependent diol dehydratase and glycerol dehydratase (2000), Arch. Microbiol., 174, 81-88.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.2.1.30 GdrA complex of GdrA-GdrB reactivates the enzyme Klebsiella oxytoca
4.2.1.30 GdrB complex of GdrA-GdrB reactivates the enzyme Klebsiella oxytoca
4.2.1.30 reactivating factor for diol dehydratase efficiently reactivates the glycerol-inactivated glycerol dehydratase in the presence of ATP, Mg2+ and adenosylcobalamin Klebsiella oxytoca
4.2.1.30 reactivating factor for diol dehydratase reactivates the glycerol-inactivated glycerol dehydratase in the presence of ATP, Mg2+ and adenosylcobalamin with only little efficiency Klebsiella pneumoniae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.28 expression in Escherichia coli Klebsiella pneumoniae
4.2.1.28 expression in Escherichia coli Klebsiella oxytoca

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.28 glycerol reaction ceases within several min Klebsiella oxytoca
4.2.1.28 glycerol reaction ceases within several min Klebsiella pneumoniae
4.2.1.30 glycerol
-
 Klebsiella oxytoca
4.2.1.30 glycerol
-
 Klebsiella pneumoniae

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.28 Klebsiella oxytoca
-
-
-
4.2.1.28 Klebsiella pneumoniae
-
-
-
4.2.1.30 Klebsiella oxytoca
-
-
-
4.2.1.30 Klebsiella pneumoniae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.28 1,2-propanediol
-
 Klebsiella pneumoniae propanal
-
 ?
4.2.1.28 1,2-propanediol
-
 Klebsiella oxytoca propanal
-
 ?
4.2.1.28 glycerol
-
 Klebsiella pneumoniae beta-hydroxypropionaldehyde
-
 ?
4.2.1.28 glycerol
-
 Klebsiella oxytoca beta-hydroxypropionaldehyde
-
 ?
4.2.1.30 glycerol
-
 Klebsiella pneumoniae 3-hydroxypropanal + H2O
-
 ?
4.2.1.30 glycerol
-
 Klebsiella oxytoca 3-hydroxypropanal + H2O
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.1.28 coenzyme B12 adenosylcobalamin. Glycerol-inactivated enzyme undergoes reactivation in the presence of the reactivating factor, the cofactor, ATP and Mg2+ Klebsiella pneumoniae
4.2.1.28 coenzyme B12 adenosylcobalamin. Glycerol-inactivated enzyme undergoes reactivation in the presence of the reactivating factor, the cofactor, ATP and Mg2+ Klebsiella oxytoca