EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.59 | 3-octylthio-1,1,1-trifluoro-2-propanone | more inhibitory than 3-pentylthio-1,1,1-trifluoro-2-propanone and diisopropyl fluorophosphate, moderately potent inhibitor | Ips typographus | |
3.1.1.59 | 3-octylthio-1,1,1-trifluoro-2-propanone | very potent inhibitor | Tenebrio molitor | |
3.1.1.59 | 3-pentylthio-1,1,1-trifluoro-2-propanone | less inhibitory than 3-octylthio-1,1,1-trifluoro-2-propanone, more inhibitory than diisopropyl fluorophosphate | Ips typographus | |
3.1.1.59 | 3-pentylthio-1,1,1-trifluoro-2-propanone | less inhibitory than 3-octylthio-1,1,1-trifluoro-2-propanone, more inhibitory than diisopropyl fluorophosphate | Tenebrio molitor | |
3.1.1.59 | diisopropyl fluorophosphate | less inhibitory than 3-octylthio-1,1,1-trifluoro-2-propanone and 3-pentylthio-1,1,1-trifluoro-2-propanone, poor inhibitor | Ips typographus | |
3.1.1.59 | diisopropyl fluorophosphate | less inhibitory than 3-octylthio-1,1,1-trifluoro-2-propanone and 3-pentylthio-1,1,1-trifluoro-2-propanone, poor inhibitor | Tenebrio molitor | |
3.1.1.59 | additional information | not inhibited by 1% Triton X-100, IC50-values for several inhibitors | Ips typographus | |
3.1.1.59 | additional information | IC50-values for several inhibitors | Tenebrio molitor | |
3.1.1.59 | O,O-diethyl-p-nitrophenyl phosphate | poor inhibitor | Ips typographus | |
3.1.1.59 | O,O-diethyl-p-nitrophenyl phosphate | poor inhibitor | Tenebrio molitor | |
3.1.1.59 | Phenylmethylsulfonylfluoride | moderate inhibitor | Ips typographus | |
3.1.1.59 | Phenylmethylsulfonylfluoride | weak inhibitor | Tenebrio molitor |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.59 | juvenile hormone + H2O | Ips typographus | JHE catabolizes juvenile hormone | Juvenile hormone acid + methanol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.59 | Ips typographus | - |
- |
- |
3.1.1.59 | Tenebrio molitor | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.59 | from pupa, 49fold | Tenebrio molitor |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.59 | adult | whole body | Ips typographus | - |
3.1.1.59 | larva | whole body | Ips typographus | - |
3.1.1.59 | additional information | developmental profile of JHE activity with different substrates | Ips typographus | - |
3.1.1.59 | prepupa | - |
Tenebrio molitor | - |
3.1.1.59 | pupa | when induced by topical application of juvenile hormone III | Ips typographus | - |
3.1.1.59 | pupa | whole body | Tenebrio molitor | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.1.59 | additional information | - |
- |
Tenebrio molitor |
3.1.1.59 | additional information | - |
specific activities of several developmental stages for the substrates juvenile hormone III, alpha-naphthyl acetate and methyl hexylthio acetothioate | Ips typographus |
3.1.1.59 | 350 | - |
purified JHE from pupa, pH 8, 30°C | Tenebrio molitor |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.59 | alpha-naphthyl acetate + H2O | - |
Tenebrio molitor | alpha-naphthol + acetate | - |
? | |
3.1.1.59 | alpha-naphthyl acetate + H2O | specific activities of several developmental stages | Ips typographus | alpha-naphthol + acetate | - |
? | |
3.1.1.59 | juvenile hormone + H2O | JHE catabolizes juvenile hormone | Ips typographus | Juvenile hormone acid + methanol | - |
? | |
3.1.1.59 | juvenile hormone III + H2O | highest specific activity | Tenebrio molitor | juvenile hormone III acid + methanol | - |
? | |
3.1.1.59 | juvenile hormone III + H2O | specific activities of several developmental stages, highest specific activity | Ips typographus | juvenile hormone III acid + methanol | - |
? | |
3.1.1.59 | methyl hexylthio acetothioate + H2O | putative surrogate substrate for juvenile hormone | Tenebrio molitor | ? | - |
? | |
3.1.1.59 | methyl hexylthio acetothioate + H2O | putative surrogate substrate for juvenile hormone, specific activities of several developmental stages | Ips typographus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.59 | JHE | - |
Tenebrio molitor |
3.1.1.59 | JHE | - |
Ips typographus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.1.59 | 30 | - |
assay at | Tenebrio molitor |
3.1.1.59 | 30 | - |
assay at | Ips typographus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.59 | 8 | - |
assay at | Tenebrio molitor |
3.1.1.59 | 8 | - |
assay at | Ips typographus |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
3.1.1.59 | Tenebrio molitor | isoelectric focusing | - |
4.34 |
3.1.1.59 | Ips typographus | isoelectric focusing | - |
4.34 |