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Literature summary extracted from
- Kinetic mechanism and pH dependence of the kinetic parameters of Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase (2001), Arch. Biochem. Biophys., 396, 111-118.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.2.2 | D-glucose-1,6-bisphosphate | - |
Pseudomonas aeruginosa |  |
| 5.4.2.8 | D-Glucose 1,6-bisphosphate | - |
Pseudomonas aeruginosa | |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.4.2.2 | overexpression in Escherichia coli | Pseudomonas aeruginosa |
| 5.4.2.8 | overexpression in Escherichia coli | Pseudomonas aeruginosa |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.2.8 | glucose 1-phosphate | substrate inhibition of reverse reaction | Pseudomonas aeruginosa | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.2.2 | alpha-D-glucose 1-phosphate | Pseudomonas aeruginosa | - |
alpha-D-glucose 6-phosphate | - |
r | |
| 5.4.2.8 | alpha-D-mannose 1-phosphate | Pseudomonas aeruginosa | - |
alpha-D-mannose 6-phosphate | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.2.2 | Pseudomonas aeruginosa | - |
- |
- |
| 5.4.2.8 | Pseudomonas aeruginosa | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 5.4.2.8 | phosphoprotein | mutation of serine 108 where phosphorylation occurs results in phosphorylation of a different residue, so that activity is reduced only 20fold from that of wild-type | Pseudomonas aeruginosa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.2.2 | alpha-D-glucose 1-phosphate | - |
Pseudomonas aeruginosa | alpha-D-glucose 6-phosphate | - |
r | |
| 5.4.2.2 | alpha-D-mannose 1-phosphate | - |
Pseudomonas aeruginosa | alpha-D-mannose 6-phosphate | - |
r | |
| 5.4.2.8 | alpha-D-glucose 1-phosphate | - |
Pseudomonas aeruginosa | alpha-D-glucose 6-phosphate | - |
r | |
| 5.4.2.8 | alpha-D-mannose 1-phosphate | - |
Pseudomonas aeruginosa | alpha-D-mannose 6-phosphate | - |
r | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.2.2 | PMM/PGM | - |
Pseudomonas aeruginosa |
| 5.4.2.8 | PMM/PGM | - |
Pseudomonas aeruginosa |
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