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Literature summary extracted from

  • Kudo, K.; Tu, A.T.
    Characterization of hyaluronidase isolated from Agkistrodon contortrix contortrix (Southern Copperhead) venom (2001), Arch. Biochem. Biophys., 386, 154-162.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.35 extracellular
-
 Agkistrodon contortrix contortrix
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.35 59290
-
 x * 59290, mass spectrometry, x * 61000, SDS-PAGE Agkistrodon contortrix contortrix
3.2.1.35 61000
-
 x * 59290, mass spectrometry, x * 61000, SDS-PAGE Agkistrodon contortrix contortrix

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.35 Agkistrodon contortrix contortrix
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.35 from venom Agkistrodon contortrix contortrix

Reaction

EC Number Reaction Comment Organism Reaction ID
3.2.1.35 hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide endoglycosidase with exoglycosidase activity Agkistrodon contortrix contortrix
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.35 venom
-
 Agkistrodon contortrix contortrix
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.35 hyaluronan + H2O absolutely specific for Agkistrodon contortrix contortrix hexasaccharides + tetrasaccharides main products, with N-acetyl-beta-D-glucosamine at the reducing end, cleavage of beta-1,4-glycosidic linkage, not beta-1,3-glycosidic linkage ?
3.2.1.35 additional information no activity with chondroitin 4-sulfate, chondroitin 6-sulfate, dermatan sulfate, chondroitin sulfates D and E, and heparin, no activity with 4-nitrophenyl-beta-glucuronide or 4-nitrophenyl-N-acetyl-beta-glucoaminide Agkistrodon contortrix contortrix ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.35 ? x * 59290, mass spectrometry, x * 61000, SDS-PAGE Agkistrodon contortrix contortrix

Synonyms

EC Number Synonyms Comment Organism
3.2.1.35 endo-beta-N-acetylhexosaminidase
-
 Agkistrodon contortrix contortrix
3.2.1.35 hyaluronidase
-
 Agkistrodon contortrix contortrix