EC Number | Cloned (Comment) | Organism |
---|---|---|
5.3.99.5 | expression in Escherichia coli | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
5.3.99.5 | A408L | 42% of wild-type activity | Homo sapiens |
5.3.99.5 | A415V | 82% of wild-type activity | Homo sapiens |
5.3.99.5 | C480H | no activity | Homo sapiens |
5.3.99.5 | C480S | no activity | Homo sapiens |
5.3.99.5 | C480Y | no activity | Homo sapiens |
5.3.99.5 | E134D | 35% of wild-type activity | Homo sapiens |
5.3.99.5 | E135D | 123% of wild-type activity | Homo sapiens |
5.3.99.5 | E414D | 39% of wild-type activity | Homo sapiens |
5.3.99.5 | F409Y | 42% of wild-type activity | Homo sapiens |
5.3.99.5 | F411Y | 38% of wild-type activity | Homo sapiens |
5.3.99.5 | N110I | no activity | Homo sapiens |
5.3.99.5 | R137A | 2% of wild-type activity | Homo sapiens |
5.3.99.5 | R137K | 5% of wild-type activity | Homo sapiens |
5.3.99.5 | R410G | 46% of wild-type activity | Homo sapiens |
5.3.99.5 | R413K | 1% of wild-type activity | Homo sapiens |
5.3.99.5 | R478A | no activity | Homo sapiens |
5.3.99.5 | T412S | 41% of wild-type activity | Homo sapiens |
5.3.99.5 | V136A | 69% of wild-type activity | Homo sapiens |
5.3.99.5 | W133F | 2% of wild-type activity | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
5.3.99.5 | endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | Homo sapiens | - |
(5Z,13E)-(15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dienoate | i.e. TXA2 | ? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.5 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
5.3.99.5 | recombinant TXAS | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Homo sapiens | (5Z,13E)-(15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dienoate | i.e. TXA2 | ? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.5 | TXAS | - |
Homo sapiens |