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Literature summary extracted from

  • Bae, K.H.; Kim, I.C.; Kim, K.S.; Shin, Y.C.; Byun, S.M.
    The Leu-3 residue of Serratia marcescens metalloprotease inhibitor is important in inhibitory activity and binding with Serratia marcescens metalloprotease (1998), Arch. Biochem. Biophys., 352, 37-43.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.40 L3A SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 L3D SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 L3F SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 L3G SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 L3I SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 L3K SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 L3P SmaPI mutant inhibitor Serratia marcescens
3.4.24.40 SmaPI Serratia marcescens metalloprotease inhibitor, wild-type Serratia marcescens
3.4.24.40 SmaPIAddA mutant inhibitor Serratia marcescens
3.4.24.40 SmaPIDelG mutant inhibitor Serratia marcescens
3.4.24.40 SmaPIDelG1-L3 mutant inhibitor Serratia marcescens
3.4.24.40 SmaPIDelG1-S2 mutant inhibitor Serratia marcescens

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.40 Serratia marcescens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.40 azocasein + H2O
-
 Serratia marcescens ?
-
 ?
3.4.24.40 N-alpha-benzoyl-DL-arginine-p-nitroanilide + H2O artificial substrate BAPNA Serratia marcescens N-alpha-benzoyl-DL-arginine + 4-nitroaniline
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.40 Serratia marcescens metalloprotease
-
 Serratia marcescens
3.4.24.40 SMP
-
 Serratia marcescens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.24.40 0.000713
-
 SmaPI pH 7.0, 25°C, wild-type inhibitor Serratia marcescens
3.4.24.40 0.000723
-
 L3I SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.000725
-
 SmaPIDelG1 pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.000728
-
 SmaPIAddA pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.000736
-
 SmaPIDelG1-S2 pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.000791
-
 L3F SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.000903
-
 L3DSmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.000958
-
 L3P SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.00107
-
 L3G SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.00184
-
 L3K SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.00217
-
 L3D SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
3.4.24.40 0.00274
-
 SmaPIDelG1-L3 pH 7.0, 25°C, mutant inhibitor Serratia marcescens