Literature summary extracted from

Liu, J.Q.; Odani, M.; Yasuoka, T.; Dairi, T.; Itoh, N.; Kataoka, M.; Shimizu, S.; Yamada, H.
Gene cloning and overproduction of low-specificity D-threonine aldolase from Alcaligenes xylosoxidans and its application for production of a key intermediate for parkinsonism drug (2000), Appl. Microbiol. Biotechnol., 54, 44-51.

Application

EC Number	Application	Comment	Organism
4.1.2.42	medicine	efficient biocatalyst for resolution of L-X-3,4-methylenedioxyphenylserine, an intermediate for production of a therapeutic drug for Parkinson's disease	Achromobacter xylosoxidans

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.1.2.42	-	Achromobacter xylosoxidans

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.1.2.42	D-threonine	Achromobacter xylosoxidans	-	glycine + acetaldehyde	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.2.42	Achromobacter xylosoxidans	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
4.1.2.42	homogeneity	Achromobacter xylosoxidans

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
4.1.2.42	38.6	-	-	Achromobacter xylosoxidans

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.2.42	D-threonine	-	Achromobacter xylosoxidans	glycine + acetaldehyde	-	?
4.1.2.42	D-threonine	-	Achromobacter xylosoxidans	glycine + acetaldehyde	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
4.1.2.42	low specificity D-TA	acts on the D-isomer	Achromobacter xylosoxidans

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
4.1.2.42	pyridoxal 5'-phosphate	dependent	Achromobacter xylosoxidans

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Release 2023.1 (January 2023)