EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.20 | chloramphenicol | - |
Haemophilus influenzae | |
6.1.1.20 | chloramphenicol | - |
Moraxella catarrhalis | |
6.1.1.20 | chloramphenicol | - |
Staphylococcus aureus | |
6.1.1.20 | chloramphenicol | - |
Streptococcus pneumoniae | |
6.1.1.20 | Methicillin | - |
Haemophilus influenzae | |
6.1.1.20 | Methicillin | - |
Moraxella catarrhalis | |
6.1.1.20 | Methicillin | - |
Staphylococcus aureus | |
6.1.1.20 | Methicillin | - |
Streptococcus pneumoniae | |
6.1.1.20 | muciproin | - |
Escherichia coli | |
6.1.1.20 | muciproin | - |
Haemophilus influenzae | |
6.1.1.20 | muciproin | - |
Moraxella catarrhalis | |
6.1.1.20 | muciproin | - |
Staphylococcus aureus | |
6.1.1.20 | muciproin | - |
Streptococcus pneumoniae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamides | strong inhibition, several derivatives, competitive to L-phenylalanine | Escherichia coli | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamides | strong inhibition, several derivatives, competitive to L-phenylalanine, cytotoxic effect | Haemophilus influenzae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamides | strong inhibition, several derivatives, competitive to L-phenylalanine, cytotoxic effect | Moraxella catarrhalis | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamides | strong inhibition, several derivatives, competitive to L-phenylalanine, cytotoxic effect | Staphylococcus aureus | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamides | strong inhibition, several derivatives, competitive to L-phenylalanine, cytotoxic effect | Streptococcus pneumoniae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethyl-chloroindol | - |
Haemophilus influenzae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethyl-chloroindol | - |
Moraxella catarrhalis | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethyl-chloroindol | - |
Staphylococcus aureus | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethyl-chloroindol | - |
Streptococcus pneumoniae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethyl-chloroindole | - |
Escherichia coli | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethylindol | strong inhibition, competitive to L-phenylalanine, cytotoxic effects on CHO cells and bacteria | Haemophilus influenzae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethylindol | strong inhibition, competitive to L-phenylalanine, cytotoxic effects on CHO cells and bacteria | Moraxella catarrhalis | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethylindol | strong inhibition, competitive to L-phenylalanine, cytotoxic effects on CHO cells and bacteria | Staphylococcus aureus | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethylindol | strong inhibition, competitive to L-phenylalanine, cytotoxic effects on CHO cells and bacteria | Streptococcus pneumoniae | |
6.1.1.20 | phenyl-thiazolylurea-sulfonamido-aminoethylindole | strong inhibition, competitive to L-phenylalanine, cytotoxic effects on CHO cells and bacteria | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Staphylococcus aureus | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Haemophilus influenzae | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Escherichia coli | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Streptococcus pneumoniae | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Moraxella catarrhalis | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Staphylococcus aureus 133 | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Streptococcus pneumoniae G9A | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Moraxella catarrhalis 489 | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | Haemophilus influenzae Spain 7 | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.1.1.20 | Escherichia coli | - |
purified enzyme, strain CP78 and mutant relA- strain CP79 | - |
6.1.1.20 | Haemophilus influenzae | - |
clinical isolate | - |
6.1.1.20 | Haemophilus influenzae Spain 7 | - |
clinical isolate | - |
6.1.1.20 | Moraxella catarrhalis | - |
- |
- |
6.1.1.20 | Moraxella catarrhalis 489 | - |
- |
- |
6.1.1.20 | Staphylococcus aureus | - |
- |
- |
6.1.1.20 | Staphylococcus aureus 133 | - |
- |
- |
6.1.1.20 | Streptococcus pneumoniae | - |
- |
- |
6.1.1.20 | Streptococcus pneumoniae G9A | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Staphylococcus aureus | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Haemophilus influenzae | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Escherichia coli | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Streptococcus pneumoniae | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Moraxella catarrhalis | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Staphylococcus aureus 133 | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Streptococcus pneumoniae G9A | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Moraxella catarrhalis 489 | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
6.1.1.20 | ATP + L-phenylalanine + tRNAPhe | - |
Haemophilus influenzae Spain 7 | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.1.1.20 | CML33 | - |
Staphylococcus aureus |
6.1.1.20 | CML33 | - |
Haemophilus influenzae |
6.1.1.20 | CML33 | - |
Escherichia coli |
6.1.1.20 | CML33 | - |
Streptococcus pneumoniae |
6.1.1.20 | CML33 | - |
Moraxella catarrhalis |
6.1.1.20 | FRS | - |
Staphylococcus aureus |
6.1.1.20 | FRS | - |
Haemophilus influenzae |
6.1.1.20 | FRS | - |
Escherichia coli |
6.1.1.20 | FRS | - |
Streptococcus pneumoniae |
6.1.1.20 | FRS | - |
Moraxella catarrhalis |
6.1.1.20 | HSPC173 | - |
Staphylococcus aureus |
6.1.1.20 | HSPC173 | - |
Haemophilus influenzae |
6.1.1.20 | HSPC173 | - |
Escherichia coli |
6.1.1.20 | HSPC173 | - |
Streptococcus pneumoniae |
6.1.1.20 | HSPC173 | - |
Moraxella catarrhalis |
6.1.1.20 | L-Phenylalanyl-tRNA synthetase | - |
Staphylococcus aureus |
6.1.1.20 | L-Phenylalanyl-tRNA synthetase | - |
Haemophilus influenzae |
6.1.1.20 | L-Phenylalanyl-tRNA synthetase | - |
Escherichia coli |
6.1.1.20 | L-Phenylalanyl-tRNA synthetase | - |
Streptococcus pneumoniae |
6.1.1.20 | L-Phenylalanyl-tRNA synthetase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanine translase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanine translase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanine translase | - |
Escherichia coli |
6.1.1.20 | Phenylalanine translase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanine translase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanine--tRNA ligase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanine--tRNA ligase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanine--tRNA ligase | - |
Escherichia coli |
6.1.1.20 | Phenylalanine--tRNA ligase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanine--tRNA ligase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanine-tRNA synthetase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanine-tRNA synthetase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanine-tRNA synthetase | - |
Escherichia coli |
6.1.1.20 | Phenylalanine-tRNA synthetase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanine-tRNA synthetase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanyl transfer ribonucleic acid synthetase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanyl transfer ribonucleic acid synthetase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanyl transfer ribonucleic acid synthetase | - |
Escherichia coli |
6.1.1.20 | Phenylalanyl transfer ribonucleic acid synthetase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanyl transfer ribonucleic acid synthetase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanyl-transfer ribonucleate synthetase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanyl-transfer ribonucleate synthetase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanyl-transfer ribonucleate synthetase | - |
Escherichia coli |
6.1.1.20 | Phenylalanyl-transfer ribonucleate synthetase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanyl-transfer ribonucleate synthetase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanyl-transfer RNA ligase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanyl-transfer RNA ligase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanyl-transfer RNA ligase | - |
Escherichia coli |
6.1.1.20 | Phenylalanyl-transfer RNA ligase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanyl-transfer RNA ligase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanyl-transfer RNA synthetase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanyl-transfer RNA synthetase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanyl-transfer RNA synthetase | - |
Escherichia coli |
6.1.1.20 | Phenylalanyl-transfer RNA synthetase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanyl-transfer RNA synthetase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanyl-tRNA ligase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanyl-tRNA ligase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanyl-tRNA ligase | - |
Escherichia coli |
6.1.1.20 | Phenylalanyl-tRNA ligase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanyl-tRNA ligase | - |
Moraxella catarrhalis |
6.1.1.20 | Phenylalanyl-tRNA synthetase | - |
Staphylococcus aureus |
6.1.1.20 | Phenylalanyl-tRNA synthetase | - |
Haemophilus influenzae |
6.1.1.20 | Phenylalanyl-tRNA synthetase | - |
Escherichia coli |
6.1.1.20 | Phenylalanyl-tRNA synthetase | - |
Streptococcus pneumoniae |
6.1.1.20 | Phenylalanyl-tRNA synthetase | - |
Moraxella catarrhalis |
6.1.1.20 | PheRS | - |
Staphylococcus aureus |
6.1.1.20 | PheRS | - |
Haemophilus influenzae |
6.1.1.20 | PheRS | - |
Escherichia coli |
6.1.1.20 | PheRS | - |
Streptococcus pneumoniae |
6.1.1.20 | PheRS | - |
Moraxella catarrhalis |
6.1.1.20 | Synthetase, phenylalanyl-transfer ribonucleate | - |
Staphylococcus aureus |
6.1.1.20 | Synthetase, phenylalanyl-transfer ribonucleate | - |
Haemophilus influenzae |
6.1.1.20 | Synthetase, phenylalanyl-transfer ribonucleate | - |
Escherichia coli |
6.1.1.20 | Synthetase, phenylalanyl-transfer ribonucleate | - |
Streptococcus pneumoniae |
6.1.1.20 | Synthetase, phenylalanyl-transfer ribonucleate | - |
Moraxella catarrhalis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.20 | ATP | - |
Staphylococcus aureus | |
6.1.1.20 | ATP | - |
Haemophilus influenzae | |
6.1.1.20 | ATP | - |
Escherichia coli | |
6.1.1.20 | ATP | - |
Streptococcus pneumoniae | |
6.1.1.20 | ATP | - |
Moraxella catarrhalis |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.1.1.20 | additional information | - |
additional information | - |
Staphylococcus aureus | |
6.1.1.20 | additional information | - |
additional information | - |
Haemophilus influenzae | |
6.1.1.20 | additional information | - |
additional information | - |
Escherichia coli | |
6.1.1.20 | additional information | - |
additional information | - |
Streptococcus pneumoniae | |
6.1.1.20 | additional information | - |
additional information | - |
Moraxella catarrhalis | |
6.1.1.20 | 0.000021 | - |
phenyl-thiazolylurea-sulfonamido-aminoethylindole | pH 7.6, 22°C | Escherichia coli |