Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Thompson, H.R.; Jones, G.M.; Narkewicz, M.R.
    Ontogeny of hepatic enzymes involved in serine- and folate-dependent one-carbon metabolism in rabbits (2001), Am. J. Physiol., 280, G873-G878.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.3.2 cytosol
-
 Oryctolagus cuniculus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.3.2 ATP + 5-formyltetrahydrofolate Oryctolagus cuniculus enzyme plays a central role in the regulation of folate-dependent, one-carbon metabolism ADP + phosphate + 5,10-methenyltetrahydrofolate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.3.2 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.3.2 brain increase during development Oryctolagus cuniculus
-
6.3.3.2 liver low activity in fetus, maximum at age 3 weeks, and again decline to moderate adult level Oryctolagus cuniculus
-
6.3.3.2 placenta low activity Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.3.2 0.00006
-
 placenta Oryctolagus cuniculus
6.3.3.2 0.00026
-
 postweaning, brain Oryctolagus cuniculus
6.3.3.2 0.00032
-
 kidney Oryctolagus cuniculus
6.3.3.2 0.00036
-
 fetal liver Oryctolagus cuniculus
6.3.3.2 0.0011
-
 adult liver Oryctolagus cuniculus
6.3.3.2 0.0015
-
 3 weeks old liver Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.3.2 ATP + 5-formyltetrahydrofolate
-
 Oryctolagus cuniculus ADP + phosphate + 5,10-methenyltetrahydrofolate
-
 ?
6.3.3.2 ATP + 5-formyltetrahydrofolate enzyme plays a central role in the regulation of folate-dependent, one-carbon metabolism Oryctolagus cuniculus ADP + phosphate + 5,10-methenyltetrahydrofolate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.3.2 5-FCL
-
 Oryctolagus cuniculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
6.3.3.2 30
-
 assay at Oryctolagus cuniculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3.3.2 7.4
-
 assay at Oryctolagus cuniculus