Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Defer, N.; Best-Belpomme, M.; Hanoune, J.
    Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase (2000), Am. J. Physiol., 279, F400-F416.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.1 forskolin
-
 Mus musculus
4.6.1.1 additional information isoenzyme AC9 is not activated by forskolin Mus musculus

Protein Variants

EC Number Protein Variants Comment Organism
4.6.1.1 Y1082L mutation in AC9 confers both binding and activation by forskolin Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.1 membrane
-
 Gallus gallus 16020
-
4.6.1.1 membrane
-
 Mus musculus 16020
-
4.6.1.1 membrane
-
 Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.1 ATP Gallus gallus
-
 3',5'-cyclic AMP + diphosphate
-
 ?
4.6.1.1 ATP Mus musculus
-
 3',5'-cyclic AMP + diphosphate
-
 ?
4.6.1.1 ATP Rattus norvegicus
-
 3',5'-cyclic AMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.1 Gallus gallus
-
 isoenzyme AC5
-
4.6.1.1 Mus musculus
-
-
-
4.6.1.1 Rattus norvegicus
-
 isoenzymes AC6, AC5, AC4, AC 7 and AC 9
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.1 ATP
-
 Gallus gallus 3',5'-cyclic AMP + diphosphate
-
 ?
4.6.1.1 ATP
-
 Mus musculus 3',5'-cyclic AMP + diphosphate
-
 ?
4.6.1.1 ATP
-
 Rattus norvegicus 3',5'-cyclic AMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.1 AC
-
 Gallus gallus
4.6.1.1 AC
-
 Rattus norvegicus
4.6.1.1 AC9
-
 Mus musculus
4.6.1.1 adenylyl cyclase
-
 Gallus gallus
4.6.1.1 adenylyl cyclase
-
 Mus musculus
4.6.1.1 adenylyl cyclase
-
 Rattus norvegicus