BRENDA - Enzyme Database

The structure and domain organization of Escherichia coli isocitrate lyase

Britton, K.L.; Abeysinghe, I.S.B.; Baker, P.J.; Barynin, V.; Diehl, P.; Langridge, S.J.; McFadden, B.A.; Sedelnikova, S.E.; Stillman, T.J.; Weeradechapon, K.; Rice, D.W.; Acta Crystallogr. Sect. D D57, 1209-1218 (2001)

Data extracted from this reference:

Crystallization (Commentary)
EC Number
Crystallization
Organism
4.1.3.1
hanging drop vapor diffusion method
Escherichia coli
Engineering
EC Number
Amino acid exchange
Commentary
Organism
4.1.3.1
A219C
similar catalytic properties as the wild-type enzyme
Escherichia coli
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.1.3.1
cytoplasm
-
Escherichia coli
5737
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.3.1
isocitrate
Escherichia coli
first step in glyoxylate-bypass pathway
succinate + glyoxylate
-
Escherichia coli
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.3.1
Escherichia coli
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.1.3.1
-
Escherichia coli
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.3.1
isocitrate
-
649253
Escherichia coli
succinate + glyoxylate
-
649253
Escherichia coli
?
4.1.3.1
isocitrate
first step in glyoxylate-bypass pathway
649253
Escherichia coli
succinate + glyoxylate
-
649253
Escherichia coli
?
Subunits
EC Number
Subunits
Commentary
Organism
4.1.3.1
tetramer
monomers are identical, crystallization experiments
Escherichia coli
Crystallization (Commentary) (protein specific)
EC Number
Crystallization
Organism
4.1.3.1
hanging drop vapor diffusion method
Escherichia coli
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
4.1.3.1
A219C
similar catalytic properties as the wild-type enzyme
Escherichia coli
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.1.3.1
cytoplasm
-
Escherichia coli
5737
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.3.1
isocitrate
Escherichia coli
first step in glyoxylate-bypass pathway
succinate + glyoxylate
-
Escherichia coli
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.1.3.1
-
Escherichia coli
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.3.1
isocitrate
-
649253
Escherichia coli
succinate + glyoxylate
-
649253
Escherichia coli
?
4.1.3.1
isocitrate
first step in glyoxylate-bypass pathway
649253
Escherichia coli
succinate + glyoxylate
-
649253
Escherichia coli
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
4.1.3.1
tetramer
monomers are identical, crystallization experiments
Escherichia coli