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Literature summary extracted from

  • Bolger, M.B.; Swenson, S.; Markland, F.S., Jr.
    Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C (2001), AAPS Pharmsci., 3, E16.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.4.24.72 medicine development of more effective therapeutic approaches for treating occlusive thrombotic diseases, potential clinical interest in fibrolase for pharmacologic dissolution of an established thrombus Agkistrodon contortrix contortrix

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.72 Zn2+ contains 1 mole of zinc per mole of protein Agkistrodon contortrix contortrix

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.72 23000
-
-
 Agkistrodon contortrix contortrix

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.72 Fibrin + H2O Agkistrodon contortrix contortrix
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.72 Agkistrodon contortrix contortrix P28891 southern copperhead snake
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.72 Fibrin + H2O
-
 Agkistrodon contortrix contortrix ?
-
 ?
3.4.24.72 additional information fibrolase identified in multiple isoforms Agkistrodon contortrix contortrix ?
-
 ?

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.4.24.72 Agkistrodon contortrix contortrix
-
-
 6.8