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Literature summary extracted from

  • Takikawa, S.; Curtius, H.Ch.; Redweik, U.; Ghisla, S.
    Purification of 6-pyruvoyl-tetrahydropterin synthase from human liver (1986), Biochem. Biophys. Res. Commun., 134, 646-651.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.3.12 19000
-
x * 19000, SDS-PAGE Homo sapiens
4.2.3.12 19000
-
4 * 19000, SDS-PAGE Homo sapiens
4.2.3.12 83000
-
-
Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.12 7,8-dihydroneopterin triphosphate Homo sapiens assay at 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.12 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
4.2.3.12 glycoprotein
-
Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.3.12 ammonium sulfate precipitation, hydroxyapatite column, gel filtration, DEAE-Fractogel 650S column, SDS-PAGE Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.12 liver
-
Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
4.2.3.12 -20ºC and -70ºC, Tris HCl, several months, stable Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.12 7,8-dihydroneopterin triphosphate
-
Homo sapiens 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
?
4.2.3.12 7,8-dihydroneopterin triphosphate assay at Homo sapiens 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
?

Subunits

EC Number Subunits Comment Organism
4.2.3.12 ? x * 19000, SDS-PAGE Homo sapiens
4.2.3.12 tetramer 4 * 19000, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.2.3.12 37
-
assay at Homo sapiens