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Literature summary extracted from

  • Butler, M.J.; Lazarovits, G.; Higgins, V.J.; Lachance, M.A.
    Partial purification and characterization of a dehydratase associated with the pentaketide melanogenesis pathway of Phaeococcomyces sp. and other fungi (1988), Exp. Mycol., 12, 367-376.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.94 2
-
 Scytalone 25°C Phaeococcomyces sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.94 63000
-
 PAGE Phaeococcomyces sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.94 scytalone Alternaria solani
-
 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone Verticillium albo-atrum
-
 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone Verticillium dahliae
-
 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone Phaeococcomyces sp.
-
 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone Cladosporium cucumerinum
-
 1,3,8-trihydroxynaphthalene + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.94 Alternaria solani
-
-
-
4.2.1.94 Cladosporium cucumerinum
-
-
-
4.2.1.94 no activity in yeast extracts that do not form pentaketide melanins
-
-
-
4.2.1.94 Phaeococcomyces sp.
-
-
-
4.2.1.94 Verticillium albo-atrum
-
 not in extracts from organisms that had not yet formed melanin
-
4.2.1.94 Verticillium dahliae
-
 not in extracts from organisms that had not yet formed melanin
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
4.2.1.94 no modification no glycoprotein Phaeococcomyces sp.

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.94 partial Phaeococcomyces sp.

Storage Stability

EC Number Storage Stability Organism
4.2.1.94 -20°C, stable for 3 months Phaeococcomyces sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.94 scytalone
-
 Alternaria solani 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone
-
 Verticillium albo-atrum 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone
-
 Verticillium dahliae 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone
-
 Phaeococcomyces sp. 1,3,8-trihydroxynaphthalene + H2O
-
 ?
4.2.1.94 scytalone
-
 Cladosporium cucumerinum 1,3,8-trihydroxynaphthalene + H2O
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.94 7.5
-
 maximal activity under anaerobic conditions Phaeococcomyces sp.

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.2.1.94 6.5 8 pH 6.5: about 65% of maximum activity, pH 8: about 60% of maximum activity Phaeococcomyces sp.