EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.22.B36 | nucleus | at cleavage cycles 8 and 9, when nuclei reach the egg surface, calpain is localized between the nuclei at the surface beneath the precleavage furrows. Calpain condenses specifically at the edge of and between actin caps that underlie the plasma membrane immediately above each nucleus | Drosophila melanogaster | 5634 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.B36 | peptide + H2O | Drosophila melanogaster | calpain is involved in the dynamic changes in the embryonic cytoskeleton, especially actin-related structures, during early embryogenesis prior to cellularization | hydrolyzed peptide | - |
? | |
3.4.22.B36 | peptide + H2O | Drosophila melanogaster Canton-S | calpain is involved in the dynamic changes in the embryonic cytoskeleton, especially actin-related structures, during early embryogenesis prior to cellularization | hydrolyzed peptide | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.B36 | Drosophila melanogaster | Q11002 | - |
- |
3.4.22.B36 | Drosophila melanogaster Canton-S | Q11002 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.B36 | embryo | calpain is first detected near the anterior pole and in posterior region of the embryo just after fertilization. The anterior calpain disappears during the cleavage cycles. On the other hand, the posterior calpain moved to the posterior pole when polar buds are formed, and condenses just below the pole cells. At cleavage cycles 8 and 9, when nuclei reach the egg surface, calpain is localized between the nuclei at the surface beneath the precleavage furrows. Calpain condenses specifically at the edge of and between actin caps that underlie the plasma membrane immediately above each nucleus | Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.B36 | peptide + H2O | calpain is involved in the dynamic changes in the embryonic cytoskeleton, especially actin-related structures, during early embryogenesis prior to cellularization | Drosophila melanogaster | hydrolyzed peptide | - |
? | |
3.4.22.B36 | peptide + H2O | calpain is involved in the dynamic changes in the embryonic cytoskeleton, especially actin-related structures, during early embryogenesis prior to cellularization | Drosophila melanogaster Canton-S | hydrolyzed peptide | - |
? |