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Literature summary extracted from
- The sodium pump glutaconyl-CoA decarboxylase from Acidaminococcus fermentans. Specific cleavage by n-alkanols (1986), Eur. J. Biochem., 156, 251-257.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.4.5 | biotin | Km: 40 mM | Acidaminococcus fermentans |  |
| 7.2.4.5 | biotin | biotinyl enzyme | Acidaminococcus fermentans | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.4.5 | additional information | with increasing chain length, sodium ions prevent inactivation, Li+ is ten times less effective than Na+ | Acidaminococcus fermentans |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 7.2.4.5 | 30000 | - |
x * 120000, alpha, biotin carrier + x * 60000, beta, carboxytransferase, carboxylase + x * 30000, gamma, sodium pump, SDS-PAGE | Acidaminococcus fermentans |
| 7.2.4.5 | 60000 | - |
x * 120000, alpha, biotin carrier + x * 60000, beta, carboxytransferase, carboxylase + x * 30000, gamma, sodium pump, SDS-PAGE | Acidaminococcus fermentans |
| 7.2.4.5 | 120000 | - |
x * 120000, alpha, biotin carrier + x * 60000, beta, carboxytransferase, carboxylase + x * 30000, gamma, sodium pump, SDS-PAGE | Acidaminococcus fermentans |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.4.5 | glutaconyl-CoA + Na+[side 1] | Acidaminococcus fermentans | - |
but-2-enoyl-CoA + CO2 + Na+[side 2] | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.2.4.5 | Acidaminococcus fermentans | - |
ATCC 25085 | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.4.5 | 4-carboxybut-2-enoyl-CoA + Na+[side 1] | - |
Acidaminococcus fermentans | but-2-enoyl-CoA + CO2 + Na+[side 2] | - |
? | |
| 7.2.4.5 | glutaconyl-CoA + Na+[side 1] | - |
Acidaminococcus fermentans | but-2-enoyl-CoA + CO2 + Na+[side 2] | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.2.4.5 | ? | x * 120000, alpha, biotin carrier + x * 60000, beta, carboxytransferase, carboxylase + x * 30000, gamma, sodium pump, SDS-PAGE | Acidaminococcus fermentans |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.4.5 | biotin | Km: 40 mM | Acidaminococcus fermentans | |
| 7.2.4.5 | biotin | biotinyl enzyme | Acidaminococcus fermentans | |
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