EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
4.2.3.6 | C146A | complete loss of activity | Fusarium sporotrichioides |
4.2.3.6 | C190A | significantly reduced enzymatic activity | Fusarium sporotrichioides |
4.2.3.6 | additional information | hybrid of enzyme from both organisms, site directed mutagenesis of hybrid | Fusarium sambucinum |
4.2.3.6 | additional information | hybrid of enzyme from both organisms, site directed mutagenesis of hybrid | Fusarium sporotrichioides |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.6 | additional information | identification of active site residues by site-directed mutagenesis | Fusarium sporotrichioides |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.6 | (E,E)-farnesyl diphosphate | Fusarium sambucinum | - |
trichodiene + diphosphate | - |
? | |
4.2.3.6 | (E,E)-farnesyl diphosphate | Fusarium sporotrichioides | - |
trichodiene + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.3.6 | Fusarium sambucinum | - |
- |
- |
4.2.3.6 | Fusarium sporotrichioides | - |
recombinant enzyme from Escherichia coli BL21 DE3/pZW03 | - |
4.2.3.6 | Fusarium sporotrichioides | - |
mutant C146A and C190A constructed by site-directed mutagenesis | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.6 | (E,E)-farnesyl diphosphate | - |
Fusarium sambucinum | trichodiene + diphosphate | - |
? | |
4.2.3.6 | (E,E)-farnesyl diphosphate | - |
Fusarium sporotrichioides | trichodiene + diphosphate | - |
? |