EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.23.16 | eIF4GI + H2O | Human immunodeficiency virus 1 | perhaps cleavage of eIF4G is an event that contributes to a more efficient translation of the genomic HIV-1 mRNA, proteolysis of eIF4GI inhibits protein synthesis directed by capped mRNAs but allows internal ribosome entry site-driven translation, purified enzyme cleaves at positions 678-679, 681-682 and 1086-1087, separating the three domains of the initiation factor | ? | - |
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EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.23.16 | Human immunodeficiency virus 1 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.23.16 | eIF4GI + H2O | perhaps cleavage of eIF4G is an event that contributes to a more efficient translation of the genomic HIV-1 mRNA, proteolysis of eIF4GI inhibits protein synthesis directed by capped mRNAs but allows internal ribosome entry site-driven translation, purified enzyme cleaves at positions 678-679, 681-682 and 1086-1087, separating the three domains of the initiation factor | Human immunodeficiency virus 1 | ? | - |
? | |
3.4.23.16 | elF4GI + H2O | purified enzyme cleaves at positions 678-679, 681-682 and 1086-1087, separating the three domains of the initiation factor | Human immunodeficiency virus 1 | additional information | - |
? |