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Literature summary extracted from

  • Sommergruber, W.; Casari, G.; Fessl, F.; Seipelt, J.; Skern, T.
    The 2A proteinase of human rhinovirus is a zinc containing enzyme (1994), Virology, 204, 815-818.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.29 human rhinovirus type 2 Human rhinovirus sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.29 additional information metal-chelating agent Human rhinovirus sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.29 Zn2+ Zn2+-depleted enzyme is reactivated by Zn2+, not Co2+ or Ni2+ Human rhinovirus sp.
3.4.22.29 Zn2+ Zn2+ is not involved in catalysis but is required for generation of an active enzyme Human rhinovirus sp.
3.4.22.29 Zn2+ zinc-containing cysteine proteinase, atom emission spectroscopy: 1 mol/mol enzyme Human rhinovirus sp.

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.29 Human rhinovirus sp.
-
 serotypes 2
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.29 recombinant enzyme Human rhinovirus sp.

Storage Stability

EC Number Storage Stability Organism
3.4.22.29 4°C, in 5% v/v glycerol, long-term storage Human rhinovirus sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.29 Thr-Arg-Pro-Ile-Ile-Thr-Thr-Ala-Gly-Pro-Ser-Asp-Met-Tyr-Val-His + H2O
-
 Human rhinovirus sp. Thr-Arg-Pro-Ile-Ile-Thr-Thr-Ala + Gly-Pro-Ser-Asp-Met-Tyr-Val-His
-
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