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Literature summary extracted from

  • Guo, Z.; Xian, M.; Zhang, W.; McGill, A.; Wang, P.G.
    N-nitrosoanilines: a new class of caspase-3 inhibitors (2001), Bioorg. Med. Chem., 9, 99-106.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.56 m-(Ac-L-Asp-L-Val-NH)-N-nitroso-N-phenylglycine
-
 Homo sapiens
3.4.22.56 N-acetyl-L-alpha-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-[[(4-methylphenyl)(nitroso)amino]methyl]ethyl]-L-alaninamide
-
 Homo sapiens
3.4.22.56 NO
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.56 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.56 acetyl-VDQMDGW-amide + H2O preferred peptide substrate Homo sapiens ?
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.22.56 0.002
-
 N-acetyl-L-alpha-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-[[(4-methylphenyl)(nitroso)amino]methyl]ethyl]-L-alaninamide pH 7.5, 30°C Homo sapiens
3.4.22.56 0.022
-
 m-(Ac-L-Asp-L-Val-NH)-N-nitroso-N-phenylglycine pH 7.5, 37°C Homo sapiens