Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bourgeois, L.; Brillard-Bourdet, M.; Deperthes, D.; Juliano, M.A.; Juliano, L.; Tremblay, R.R.; Dube, J.Y.; Gauthier, F.
    Serpin-derived peptide substrates for investigating the substrate specificity of human tissue kallikreins hK1 and hK2 (1997), J. Biol. Chem., 272, 29590-29595.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.21.77 medicine enzyme is a marker for prostatic disease Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.77 Fibronectin + H2O Homo sapiens enzyme participates in sperm liquefaction by cleaving fibronectin and semenogelins, the major components of the seminal vesicle coagulum after ejaculation ?
-
 ?
3.4.21.77 polypeptide + H2O Homo sapiens enzyme possibly is involved in the processing of insulin-like growth factor binding protein 3 peptides
-
 ?
3.4.21.77 semenogelin + H2O Homo sapiens enzyme participates in sperm liquefaction by cleaving fibronectin and semenogelins, the major components of the seminal vesicle coagulum after ejaculation semenogelin fractions
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.77 Homo sapiens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.4.21.77 Preferential cleavage: -Tyr-/- enzyme shows chymotrypsin-like activity Homo sapiens
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.77 prostate
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.77 Fibronectin + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.77 Fibronectin + H2O enzyme participates in sperm liquefaction by cleaving fibronectin and semenogelins, the major components of the seminal vesicle coagulum after ejaculation Homo sapiens ?
-
 ?
3.4.21.77 polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
3.4.21.77 polypeptide + H2O enzyme possibly is involved in the processing of insulin-like growth factor binding protein 3 Homo sapiens peptides
-
 ?
3.4.21.77 semenogelin + H2O
-
 Homo sapiens semenogelin fragments
-
 ?
3.4.21.77 semenogelin + H2O enzyme participates in sperm liquefaction by cleaving fibronectin and semenogelins, the major components of the seminal vesicle coagulum after ejaculation Homo sapiens semenogelin fractions
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.77 K3
-
 Homo sapiens
3.4.21.77 prostate-specific antigen
-
 Homo sapiens