Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Saedi, M.S.; Zhu, Z.; Marker, K.; Liu, R.S.; Carpenter, P.M.; Rittenhouse, H.; Mikolajczyk, S.D.
    Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells (2001), Int. J. Cancer, 94, 558-563.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.21.35 medicine enzyme complexed with prostate protease inhibitor-6 may be a naturally occuring marker of tissue damage and necrosis associated with neoplasia Homo sapiens
3.4.21.35 medicine enzyme is a diagnostic marker for prostate cancer Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.35 protease inhibitor-6 from prostate, increased expression in prostate carcinoma; intracellular serine protease inhibitor with both antitrypsin and antichymotrypsin activity; rapid complex formation with the enzyme, involved in neoplastic progression Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.35 extracellular secretion Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.35 polypeptide + H2O Homo sapiens
-
 peptides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.35 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.35 prostate cancer cell increased expression Homo sapiens
-
3.4.21.35 prostate gland
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.35 polypeptide + H2O
-
 Homo sapiens peptides
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.35 K2
-
 Homo sapiens