EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.35 | antipain | weak | Homo sapiens | |
3.4.21.35 | leupeptin | weak | Homo sapiens | |
3.4.21.35 | Protein C inhibitor | - |
Homo sapiens | |
3.4.21.35 | Zn2+ | - |
Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.35 | 0.02 | - |
Ala-Arg-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens | |
3.4.21.35 | 0.04 | - |
Pro-Phe-Arg-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens | |
3.4.21.35 | 0.048 | - |
Val-Pro-Arg-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens | |
3.4.21.35 | 0.071 | - |
Leu-Leu-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.35 | additional information | Homo sapiens | likely the physiological activator of the zymogen form of prostate-specific antigen in the prostate | ? | - |
? | |
3.4.21.35 | polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.35 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.35 | prostate gland | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.35 | Ala-Ala-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Ala-Ala-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | Ala-Arg-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Ala-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | Fibronectin + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.35 | Leu-Leu-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Leu-Leu-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | additional information | - |
Homo sapiens | ? | - |
? | |
3.4.21.35 | additional information | likely the physiological activator of the zymogen form of prostate-specific antigen in the prostate | Homo sapiens | ? | - |
? | |
3.4.21.35 | polypeptide + H2O | - |
Homo sapiens | peptides | - |
? | |
3.4.21.35 | Pro-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Pro-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | Pro-Phe-Arg-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Pro-Phe-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | pro-urokinase + H2O | - |
Homo sapiens | urokinase | - |
? | |
3.4.21.35 | semenogelin I + H2O | - |
Homo sapiens | semenogelin I fragments | - |
? | |
3.4.21.35 | semenogelin II + H2O | - |
Homo sapiens | semenogelin II fragments | - |
? | |
3.4.21.35 | Val-Pro-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Val-Pro-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | Val-Pro-Arg-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Val-Pro-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.35 | zymogen of prostate-specific antigen + H2O | - |
Homo sapiens | prostate-specific antigen + APLILSR | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.21.35 | 37 | - |
assay at | Homo sapiens |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.35 | 0.0267 | - |
Val-Pro-Arg-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens | |
3.4.21.35 | 0.04 | - |
Leu-Leu-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens | |
3.4.21.35 | 0.12 | - |
Ala-Arg-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens | |
3.4.21.35 | 0.917 | - |
Pro-Phe-Arg-Arg-7-amido-4-methylcoumarin | pH 7.5, 37°C | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.35 | 7.5 | - |
assay at | Homo sapiens |
3.4.21.35 | 8 | - |
- |
Homo sapiens |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.35 | 6.5 | 9.5 | pH 6.5: about 30% of maximal activity, pH 9.5: about 40% of maximal activity | Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.35 | 0.000000025 | - |
Protein C inhibitor | pH 7.5, 37°C | Homo sapiens |