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Literature summary extracted from
- Human tissue kallikrein (1988), Methods Enzymol., 163, 102-115.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.21.35 | extracellular | secretion | Homo sapiens | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.35 | polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.35 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.21.35 | to homogeneity | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.35 | intestine | small and large | Homo sapiens | - |
| 3.4.21.35 | kidney | - |
Homo sapiens | - |
| 3.4.21.35 | pancreas | - |
Homo sapiens | - |
| 3.4.21.35 | prostate gland | - |
Homo sapiens | - |
| 3.4.21.35 | salivary gland | - |
Homo sapiens | - |
| 3.4.21.35 | seminal plasma | - |
Homo sapiens | - |
| 3.4.21.35 | urine | - |
Homo sapiens | - |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.4.21.35 | -30°C, purified urinary enzyme, stable for 1 year | Homo sapiens |
| 3.4.21.35 | 20°C, purified urinary enzyme, 0.02% w/v NaN3, neutral pH, stable for more than 14 days | Homo sapiens |
| 3.4.21.35 | 4°C, purified urinary enzyme, 0.02% w/v NaN3, stable for more than 6 months | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.35 | D-Val-Leu-Arg-p-nitroanilide + H2O | - |
Homo sapiens | D-Val-Leu-Arg + p-nitroaniline | - |
? | |
| 3.4.21.35 | kininogen + H2O | - |
Homo sapiens | kinin + ? | - |
? | |
| 3.4.21.35 | low-molecular-weight kininogen + H2O | - |
Homo sapiens | kallidin + kinin | - |
? | |
| 3.4.21.35 | N-alpha-acetyl-Phe-Arg ethyl ester + H2O | - |
Homo sapiens | N-alpha-acetyl-Phe-Arg + ethanol | - |
? | |
| 3.4.21.35 | polypeptide + H2O | - |
Homo sapiens | peptides | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.35 | 37 | - |
assay at | Homo sapiens |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.35 | 2 | - |
immediate irreversible inactivation | Homo sapiens |
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Release 2023.1 (January 2023)
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