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Literature summary extracted from

  • Fujimoto, Y.; Suzuki, C.; Watanabe, Y.; Matsuda, Y.; Akihama, S.
    Purification and characterization of a kallikrein from human submaxillary glands (1990), Biochem. Med. Metab. Biol., 44, 218-227.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.35
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.35 PMSF
-
 Homo sapiens
3.4.21.35 tosyl-L-Lys-chloromethylketone
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.35 extracellular secretion Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.35 polypeptide + H2O Homo sapiens
-
 peptides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.35 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.35 proteolytic modification preprokallikrein consists of 262 amino acid residues Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.35 1460fold Homo sapiens
3.4.21.35 large scale Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.35 submandibular gland
-
 Homo sapiens
-
3.4.21.35 submaxillary gland
-
 Homo sapiens
-
3.4.21.35 urine
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.21.35 96.5
-
 purified enzyme Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.35 acetyl-Phe-Arg methyl ester + H2O
-
 Homo sapiens acetyl-Phe-Arg + methanol
-
 ?
3.4.21.35 D-Ile-Pro-Arg-4-nitroanilide + H2O weak activity Homo sapiens D-Ile-Pro-Arg + 4-nitroaniline
-
 ?
3.4.21.35 D-Pro-Phe-Arg-4-nitroanilide + H2O weak activity Homo sapiens D-Pro-Phe-Arg + 4-nitroaniline
-
 ?
3.4.21.35 D-Val-Leu-Arg-p-nitroanilide + H2O weak activity Homo sapiens D-Val-Leu-Arg + p-nitroaniline
-
 ?
3.4.21.35 D-Val-Leu-Lys-4-nitroanilide + H2O weak activity Homo sapiens D-Val-Leu-Lys + 4-nitroaniline
-
 ?
3.4.21.35 kininogen + H2O
-
 Homo sapiens kinin + ?
-
 ?
3.4.21.35 low-molecular-weight kininogen + H2O
-
 Homo sapiens kallidin + kinin
-
 ?
3.4.21.35 N-alpha-benzoyl-L-Arg methyl ester + H2O
-
 Homo sapiens N-alpha-benzoyl-L-Arg + methanol
-
 ?
3.4.21.35 N-alpha-benzoyl-L-Lys methyl ester + H2O
-
 Homo sapiens N-alpha-benzoyl-L-Lys + methanol
-
 ?
3.4.21.35 polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
3.4.21.35 Tosyl-Arg methyl ester + H2O
-
 Homo sapiens Tosyl-Arg + methanol
-
 ?