Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Webster, M.E.; Prado, E.S.
    Glandular kallikreins from horse and human urine and from hog pancreas (1970), Methods Enzymol., 19, 681-699.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.35 benzamidine
-
 Equus caballus
3.4.21.35 benzamidine
-
 Homo sapiens
3.4.21.35 benzamidine
-
 Sus scrofa
3.4.21.35 Co2+
-
 Sus scrofa
3.4.21.35 Cu2+
-
 Sus scrofa
3.4.21.35 diisopropyl fluorophosphate
-
 Equus caballus
3.4.21.35 diisopropyl fluorophosphate
-
 Homo sapiens
3.4.21.35 diisopropyl fluorophosphate
-
 Sus scrofa
3.4.21.35 Egg white
-
 Homo sapiens
3.4.21.35 Hg2+
-
 Sus scrofa
3.4.21.35 Mn2+
-
 Sus scrofa
3.4.21.35 Ni2+
-
 Sus scrofa
3.4.21.35 pancratic inhibitor
-
 Sus scrofa
3.4.21.35 Trasylol
-
 Equus caballus
3.4.21.35 Trasylol
-
 Homo sapiens
3.4.21.35 Trasylol
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.35 extracellular secretion Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.21.35 Ca2+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
3.4.21.35 K+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
3.4.21.35 Li+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
3.4.21.35 Na+
-
 Homo sapiens
3.4.21.35 Na+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
3.4.21.35 Rb+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.35 25200
-
 equilibrium sedimentation Sus scrofa
3.4.21.35 40500
-
 short column equilibrium sedimentation Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.35 polypeptide + H2O Homo sapiens
-
 peptides
-
 ?
3.4.21.35 polypeptide + H2O Sus scrofa
-
 peptides
-
 ?
3.4.21.35 polypeptide + H2O Equus caballus
-
 peptides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.35 Equus caballus
-
-
-
3.4.21.35 Homo sapiens
-
-
-
3.4.21.35 Sus scrofa
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.35 side-chain modification
-
 Homo sapiens
3.4.21.35 side-chain modification the glycoprotein consists of 283 amino acid residues and 19-21 sugar residues Sus scrofa

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.35
-
 Homo sapiens
3.4.21.35
-
 Sus scrofa
3.4.21.35
-
 Equus caballus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.35 pancreas
-
 Homo sapiens
-
3.4.21.35 pancreas
-
 Sus scrofa
-
3.4.21.35 urine
-
 Homo sapiens
-
3.4.21.35 urine
-
 Equus caballus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.35 kininogen + H2O
-
 Homo sapiens kinin + ?
-
 ?
3.4.21.35 kininogen + H2O
-
 Sus scrofa kinin + ?
-
 ?
3.4.21.35 kininogen + H2O
-
 Equus caballus kinin + ?
-
 ?
3.4.21.35 low-molecular-weight kininogen + H2O
-
 Homo sapiens kallidin + kinin
-
 ?
3.4.21.35 low-molecular-weight kininogen + H2O
-
 Sus scrofa kallidin + kinin
-
 ?
3.4.21.35 low-molecular-weight kininogen + H2O
-
 Equus caballus kallidin + kinin
-
 ?
3.4.21.35 poly-L-Arg + H2O
-
 Equus caballus ?
-
 ?
3.4.21.35 polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
3.4.21.35 polypeptide + H2O
-
 Sus scrofa peptides
-
 ?
3.4.21.35 polypeptide + H2O
-
 Equus caballus peptides
-
 ?
3.4.21.35 salmine + H2O
-
 Equus caballus ?
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.21.35 20
-
 pH 7.0-9.5, 5 h, stable. Little loss of activity after 5 h at pH 4.4 Sus scrofa