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Literature summary extracted from

  • Nelson, P.S.; Gan, L.; Ferguson, C.; Moss, P.; Gelinas, R.; Hood, L.; Wang, K.
    Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression (1999), Proc. Natl. Acad. Sci. USA, 96, 3114-3119.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.B12 DNA sequence determination and analysis, chromosome mapping and genomic organization Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.B12 additional information enzyme contains an amino-terminal pre-propeptide sequence, indicating a potential secretory function Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.B12 polypeptide + H2O Homo sapiens enzyme is involved in degradation of extracellular matrix and activation of prostate specific antigen PSA and other proteases peptides
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B12 Homo sapiens Q9Y5K2 gene prostase
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.4.21.B12 proteolysis of polypeptides enzyme is a serine protease Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.B12 additional information enzyme shows a prostate-restricted expression Homo sapiens
-
3.4.21.B12 prostate restricted expression in hormonally responsive normal and neoplastic epithelial tissue, but not in prostate stromal constituents Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B12 polypeptide + H2O
-
Homo sapiens peptides
-
?
3.4.21.B12 polypeptide + H2O enzyme is involved in degradation of extracellular matrix and activation of prostate specific antigen PSA and other proteases Homo sapiens peptides
-
?