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Literature summary extracted from

  • Matsumoto-Miyai, K.; Kitagawa, R.; Ninomiya, A.; Momota, Y.; Yoshida, S.; Shiosaka, S.
    Decidualization induces the expression and activation of an extracellular protease neuropsin in mouse uterus (2002), Biol. Reprod., 67, 1414-1418.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.118 additional information enzyme is induced and activated by uterine decidualization Mus musculus

Application

EC Number Application Comment Organism
3.4.21.118 biotechnology enzyme might contribute to the remodeling of extracellular components after decidualization Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.118 extracellular secreted Mus musculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.118 polypeptide + H2O Mus musculus
-
 peptides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.118 Mus musculus Q61955
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.4.21.118 cleavage of amide substrates following the basic amino acids Arg or Lys at the P1 position, with a preference for Arg over Lys enzyme is a trypsin-type serine protease Mus musculus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.118 uterus low activity in nonpregnant uteri, increased activity in pregnant uteri, highest at midgestational period Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.118 polypeptide + H2O
-
 Mus musculus peptides
-
 ?
3.4.21.118 tert-butyloxycarbonyl-Val-Pro-Arg-4-methylcoumaryl-7-amide + H2O
-
 Mus musculus tert-butyloxycarbonyl-Val-Pro-Arg + 7-amino-4-methylcoumarin
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.21.118 37
-
 assay at Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.118 7.4
-
 assay at Mus musculus