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Literature summary extracted from
- Evidence for an essential histidine in carboxypeptidase Y. Reaction with the chloromethyl ketone derivative of benzyloxycarbonyl-L-phenylalanine (1975), J. Biol. Chem., 250, 5221-5226.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.16.5 | benzyloxycarbonyl-L-phenylalanyl chloromethane | diisopropylphosphorofluoridate-inactivated enzyme does not react with the inhibitor | Saccharomyces cerevisiae |  |
| 3.4.16.5 | diisopropyl fluorophosphate | benzyloxycarbonyl-L-phenylalanyl chloromethane-inhibited enzyme does not react with the inhibitor | Saccharomyces cerevisiae | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.16.5 | Saccharomyces cerevisiae | - |
baker's yeast | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.16.5 | additional information | the mechanism involves a charge-relay system in the hydrolysis of peptide and ester substrates | Saccharomyces cerevisiae | ? | - |
? | |
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Release 2023.1 (January 2023)
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