EC Number | General Stability | Organism |
---|---|---|
3.4.13.20 | inactivation during DEAE-cellulose chromatography, slow reactivation when concentrated and stored at 4°C | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.13.20 | 75000 | - |
2 * 75000, subunits are connected by one or more disulfide bonds, SDS-PAGE | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.13.20 | anserine + H2O | Homo sapiens | splitting in the blood stream | beta-Ala + Ntau-methyl-L-histidine | - |
? | |
3.4.13.20 | carnosine + H2O | Homo sapiens | splitting in the blood stream | beta-Ala + His | - |
? | |
3.4.13.20 | homocarnosine + H2O | Homo sapiens | splitting of homocarnosine in the brain | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.13.20 | Homo sapiens | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.4.13.20 | glycoprotein | - |
Homo sapiens |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.13.20 | - |
Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.13.20 | blood serum | not in serum of other mammals | Homo sapiens | - |
3.4.13.20 | brain | - |
Homo sapiens | - |
3.4.13.20 | additional information | the enzyme activity in tissues is roughly proportional to blood content for all the tissues except brain, indicating that serum carnosinase is present in the trapped blood of these tissues | Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.4.13.20 | additional information | - |
- |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.13.20 | Ala-Ala + H2O | 11% of the activity with carnosine | Homo sapiens | Ala + Ala | - |
? | |
3.4.13.20 | Ala-His + H2O | 38% of the activity with carnosine | Homo sapiens | Ala + His | - |
? | |
3.4.13.20 | Ala-Leu + H2O | 13% of the activity with carnosine | Homo sapiens | Ala + Leu | - |
? | |
3.4.13.20 | Ala-Tyr + H2O | 8% of the activity with carnosine | Homo sapiens | Ala + Tyr | - |
? | |
3.4.13.20 | anserine + H2O | 88% of the activity with carnosine | Homo sapiens | beta-Ala + Ntau-methyl-L-histidine | - |
? | |
3.4.13.20 | anserine + H2O | splitting in the blood stream | Homo sapiens | beta-Ala + Ntau-methyl-L-histidine | - |
? | |
3.4.13.20 | beta-Ala-Ala + H2O | 10% of the activity with carnosine | Homo sapiens | beta-Ala + Ala | - |
? | |
3.4.13.20 | beta-Ala-Phe + H2O | 18% of the activity with carnosine | Homo sapiens | beta-Ala + Phe | - |
? | |
3.4.13.20 | carnosine + H2O | beta-Ala-His | Homo sapiens | beta-Ala + His | - |
? | |
3.4.13.20 | carnosine + H2O | splitting in the blood stream | Homo sapiens | beta-Ala + His | - |
? | |
3.4.13.20 | Gly-Gly + H2O | 7% of the activity with carnosine | Homo sapiens | Gly + Gly | - |
? | |
3.4.13.20 | Gly-His + H2O | 37% of the activity with carnosine | Homo sapiens | Gly + His | - |
? | |
3.4.13.20 | Gly-His-Gly + H2O | 13% of the activity with carnosine | Homo sapiens | ? | - |
? | |
3.4.13.20 | Gly-His-Lys + H2O | 7% of the activity with carnosine | Homo sapiens | ? | - |
? | |
3.4.13.20 | Gly-Leu + H2O | 21% of the activity with carnosine | Homo sapiens | Gly + Leu | - |
? | |
3.4.13.20 | homocarnosine + H2O | 11% of the activity with carnosine | Homo sapiens | ? | - |
? | |
3.4.13.20 | homocarnosine + H2O | splitting of homocarnosine in the brain | Homo sapiens | ? | - |
? | |
3.4.13.20 | Leu-Leu + H2O | 8% of the activity with carnosine | Homo sapiens | Leu + Leu | - |
? | |
3.4.13.20 | additional information | dipeptide with histidine in the C-terminal position is preferred | Homo sapiens | ? | - |
? | |
3.4.13.20 | Phe-Ala + H2O | 8% of the activity with carnosine | Homo sapiens | Phe + Ala | - |
? | |
3.4.13.20 | Ser-His + H2O | 8% of the activity with carnosine | Homo sapiens | Ser + His | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.13.20 | dimer | 2 * 75000, subunits are connected by one or more disulfide bonds, SDS-PAGE | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.13.20 | 4.4 | - |
- |
Homo sapiens |