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Literature summary extracted from

  • McIntyre, T.; Curthoys, N.P.
    Renal catabolism of glutathione. Characterization of a particulate rat renal dipeptidase that catalyzes the hydrolysis of cysteinylglycine (1982), J. Biol. Chem., 257, 11915-11921.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.13.19 bestatin no inhibition Rattus norvegicus
3.4.13.19 Cystinyl-bis-glycine inhibition above 0.2 mM, substrate below Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.13.19 0.65
-
 L-Cystinyl-bis-glycine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.13.19 membrane
-
 Rattus norvegicus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.13.19 49500
-
 2 * 49500, SDS-PAGE Rattus norvegicus
3.4.13.19 95300
-
 sedimentation equilibrium analysis Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.19 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.13.19 glycoprotein
-
 Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.13.19
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.13.19 624
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.19 L-cystinyl-bis-glycine + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.13.19 L-cystinyl-bis-glycine + H2O
-
 Rattus norvegicus L-Cys + Gly-Gly
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.13.19 dimer 2 * 49500, SDS-PAGE Rattus norvegicus