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Literature summary extracted from

  • Minami, M.; Mutoh, H.; Ohishi, N.; Honda, Z.i.; Bito, H.; Shimizu, T.
    Amino-acid sequence and tissue distribution of guinea-pig leukotriene A4 hydrolase (1995), Gene, 161, 249-251.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.3.2.6 medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Cavia porcellus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.3.2.6 mRNA is distributed in liver, brain, lung, heart, kidney, and highly expressed in the intestine and spleen Cavia porcellus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.3.2.6 68758
-
 x * 68758, calculated from amino acid sequence Cavia porcellus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.3.2.6 leukotriene A4 + H2O Cavia porcellus biosynthesis of leukotriene B4 leukotriene B4
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.6 Cavia porcellus P19602
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.6 additional information mRNA is distributed in liver, brain, lung, heart, kidney, and highly expressed in the intestine and spleen Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.6 leukotriene A4 + H2O
-
 Cavia porcellus leukotriene B4
-
 ?
3.3.2.6 leukotriene A4 + H2O biosynthesis of leukotriene B4 Cavia porcellus leukotriene B4
-
 ?

Subunits

EC Number Subunits Comment Organism
3.3.2.6 ? x * 68758, calculated from amino acid sequence Cavia porcellus