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Literature summary extracted from

  • Nathaniel, D.J.; Evans, J.F.; Leblanc, Y.; Leveille, C.; Fitzsimmons, B.J.; Ford-Hutchinson, A.W.
    Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase (1985), Biochem. Biophys. Res. Commun., 131, 827-835.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.3.2.6 medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Homo sapiens
3.3.2.6 medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.6 Leukotriene A5
-
Homo sapiens
3.3.2.6 Leukotriene A5
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.3.2.6 leukotriene A4 + H2O Homo sapiens biosynthesis of leukotriene B4 leukotriene B4
-
?
3.3.2.6 leukotriene A4 + H2O Rattus norvegicus biosynthesis of leukotriene B4 leukotriene B4
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.6 Homo sapiens
-
-
-
3.3.2.6 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.6 neutrophil
-
Homo sapiens
-
3.3.2.6 neutrophil
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.6 leukotriene A4 + H2O
-
Homo sapiens leukotriene B4
-
?
3.3.2.6 leukotriene A4 + H2O
-
Rattus norvegicus leukotriene B4
-
?
3.3.2.6 leukotriene A4 + H2O biosynthesis of leukotriene B4 Homo sapiens leukotriene B4
-
?
3.3.2.6 leukotriene A4 + H2O biosynthesis of leukotriene B4 Rattus norvegicus leukotriene B4
-
?
3.3.2.6 leukotriene A5 + H2O i.e. 5(S)-trans-5,6-oxido-7,9-trans-11,14,17-cis-eicosatetraenoic acid Homo sapiens ?
-
?
3.3.2.6 leukotriene A5 + H2O i.e. 5(S)-trans-5,6-oxido-7,9-trans-11,14,17-cis-eicosatetraenoic acid Rattus norvegicus ?
-
?