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Literature summary extracted from

  • Samuelsson, B.; Funk, C.D.
    Enzymes involved in the biosynthesis of leukotriene B4 (1989), J. Biol. Chem., 264, 19469-19472.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.3.2.6 medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Cavia porcellus
3.3.2.6 medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Homo sapiens
3.3.2.6 medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.6 leukotriene A4
-
 Cavia porcellus
3.3.2.6 leukotriene A4 suicide inactivation Homo sapiens
3.3.2.6 leukotriene A4
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.6 cytosol
-
 Cavia porcellus 5829
-
3.3.2.6 cytosol
-
 Homo sapiens 5829
-
3.3.2.6 cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.3.2.6 leukotriene A4 + H2O Homo sapiens biosynthesis of leukotriene B4 leukotriene B4
-
 ?
3.3.2.6 leukotriene A4 + H2O Rattus norvegicus biosynthesis of leukotriene B4 leukotriene B4
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.6 Cavia porcellus
-
-
-
3.3.2.6 Homo sapiens
-
-
-
3.3.2.6 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.6 erythrocyte
-
 Homo sapiens
-
3.3.2.6 leukocyte
-
 Rattus norvegicus
-
3.3.2.6 leukocyte peripheral Homo sapiens
-
3.3.2.6 liver
-
 Cavia porcellus
-
3.3.2.6 liver
-
 Homo sapiens
-
3.3.2.6 liver
-
 Rattus norvegicus
-
3.3.2.6 lung
-
 Cavia porcellus
-
3.3.2.6 lung
-
 Homo sapiens
-
3.3.2.6 lung
-
 Rattus norvegicus
-
3.3.2.6 neutrophil
-
 Homo sapiens
-
3.3.2.6 neutrophil
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.6 leukotriene A4 + H2O
-
 Cavia porcellus leukotriene B4
-
 ?
3.3.2.6 leukotriene A4 + H2O
-
 Homo sapiens leukotriene B4
-
 ?
3.3.2.6 leukotriene A4 + H2O
-
 Rattus norvegicus leukotriene B4
-
 ?
3.3.2.6 leukotriene A4 + H2O biosynthesis of leukotriene B4 Homo sapiens leukotriene B4
-
 ?
3.3.2.6 leukotriene A4 + H2O biosynthesis of leukotriene B4 Rattus norvegicus leukotriene B4
-
 ?